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KMID : 0360220200610060603
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Journal of the Korean Ophthalmological Society
2020 Volume.61 No. 6 p.603 ~ p.609
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Clinical Efficacy of Microblepharoexfoliation in Meibomian Gland Dysfunction Patients
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Byeon Hyeong-Ju
Jun Ik-Hyun
Seo Kyoung-Yul
Kim Eung-Kweon
Kim Tae-Im
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Abstract
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Purpose: To assess the clinical efficacy of microblepharoexfolication using BlephEx™ (Scope Ophthalmics, London, UK) in meibomian gland dysfunction (MGD) patients.
Methods: We performed a prospective study involving 48 eyes of 24 patients who were diagnosed with MGD. All patients were treated with BlephEx™ for 8-10 minutes, and the ocular surface disease index (OSDI), tear break-up time (TBUT), Schirmer’s I test, corneal staining score, lid margin abnormality, MGD score, and lipid thickness layer using the Lipiview II (TearScience, Morrisville, NC, USA) were assessed before treatment and after one month.
Results: Significant changes were observed after microblepharoexfoliation using BlephExTM. The TBUT improved from 2.65 ± 1.16 to 3.77 ± 1.80 after 1 month (p < 0.001) and the OSDI improved from 38.83 ± 17.13 to 18.67 ± 15.01 after 1 month (p < 0.001). Before and after 1 month of treatment, the lid margin abnormalities were 2.98 ± 1.16 and 2.50 ± 1.01 (p < 0.001) and the MGD scores were 21.60 ± 6.95 and 18.02 ± 6.68 (p = 0.001), respectively.
Conclusions: BlephExTM improved the patients’ ocular surface symptoms, MGD score, and TBUT. Using steroid eye drops, there was a synergistic effect in improvement. Therefore, using BlephExTM may be suggested as a treatment option for MGD patients.
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KEYWORD
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Biofilm, BlephExTM, Dry eye disease, Meibomian gland dysfunction, Microblepharoexfoliation
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